Skip to content
Microsystems, Electronics and Acoustics
ISSN 2523-4447 · e‑ISSN 2523-4455 Open Access · CC BY-SA 4.0
Vol. 29 · Issue 2 · 2024 Aug 4, 2024 Review articles

Deep Learning for the Detection and Classification of Diabetic Retinopathy Stages

MB
Marko Romanovych Basarab Corresponding Національний технічний університет України «Київський політехнічний інститут імені Ігоря Сікорського» Ukraine
KI
Kateryna Olehivna Ivanko Національний технічний університет України «Київський політехнічний інститут імені Ігоря Сікорського» Ukraine
Pages309642.1-309642.08 PublishedAug 4, 2024
VOL 29 · ISS 2 · 2024 View issue

Abstract

The incidence of diabetic retinopathy (DR), a complication of diabetes leading to severe vision impairment and potential blindness, has surged worldwide in recent years. This condition is considered one of the leading causes of vision loss. To improve diagnostic accuracy for DR and reduce the burden on healthcare professionals, artificial intelligence (AI) methods are increasingly implemented in medical institutions. AI-based models, in particular, are integrating more algorithms to enhance the performance of existing neural network architectures that are commercially used for DR detection. However, these neural network models still exhibit limitations, such as the need for high computational power and lower accuracy in detecting early DR stages. To overcome these challenges, developing more advanced machine learning models for precise DR detection and classification of DR stages is essential, as it would aid ophthalmologists in making accurate diagnoses. This article reviews current research on the use of deep learning in diagnosing and classifying DR and related diseases, as well as the challenges ophthalmologists face in detecting this condition and potential solutions for early-stage DR detection. This review provides information on modern approaches to DR detection using deep learning applications and discusses the issues and limitations in this area.

Keywords

References

  1. G. D. Ogle, “Global estimates of incidence of type 1 diabetes in children and adolescents: Results from the International Diabetes Federation Atlas, 10th edition”, Diabetes Research and Clinical Practice, vol. 183, p. 109083, Jan. 2022. DOI: https://doi.org/10.1016/j.diabres.2021.109083 .
  2. J. W. Yau, “Global Prevalence and Major Risk Factors of Diabetic Retinopathy”, Diabetes Care, vol. 35, no. 3, pp. 556–564, Feb. 2012. DOI: https://doi.org/10.2337/dc11-1909
  3. P. Ansari, “Diabetic Retinopathy: An Overview on Mechanisms, Pathophysiology and Pharmacotherapy”, Diabetology, vol. 3, no. 1, pp. 159–175, Feb. 2022. DOI: https://doi.org/10.3390/diabetology3010011
  4. A. R. Khyts, “Diabetic Macular Edema: Patient Management in Light of Modern Recommendations”, Ukrainian Medical Journal, Aug. 2021. [Online Publication] URL: https://umj.com.ua/uk/publikatsia-212799-diabetichnij-makulyarnij-nabryak-menedzhment-patsiyentiv-u-svitli-suchasnih-rekomendatsij
  5. A. Esteva, “Dermatologist-level classification of skin cancer with deep neural networks”, Nature, vol. 542, no. 7639, pp. 115–118, Jan. 2017. DOI: https://doi.org/10.1038/nature21056
  6. V. Gulshan, “Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs”, JAMA, vol. 316, no. 22, p. 2402, Dec. 2016. DOI: https://doi.org/10.1001/jama.2016.17216
  7. I. Goodfellow, Y. Bengio, and A. Courville, "Deep Learning.," MIT Press, 2016. ISBN: 9780262035613. URL: https://mitpress.mit.edu/9780262035613/deep-learning/
  8. S. K. Zhou, H. Greenspan, and D. Shen, "Deep Learning in Medical Image Analysis," Academic Press, 2017. URL: https://www.sciencedirect.com/book/9780128104088/deep-learning-in-medical-image-analysis .
  9. Diabetic Retinopathy Detection. Kaggle. URL: https://www.kaggle.com/c/diabetic-retinopathy-detection/data
  10. Messidor-1 Dataset. Methods to Evaluate Segmentation and Indexing Techniques in the field of Retinal Ophthalmology. URL: https://www.adcis.net/en/third-party/messidor/
  11. DRIVE: Digital Retinal Images for Vessel Extraction URL: https://drive.grand-challenge.org/
  12. STARE Dataset. Structured Analysis of the Retina. URL: https://cecas.clemson.edu/~ahoover/stare/
  13. DIARETDB1 Dataset. Standard Diabetic Retinopathy Database. URL: https://www.kaggle.com/datasets/nguyenhung1903/diaretdb1-standard-diabetic-retinopathy-database
  14. E-ophtha Dataset. ADCIS. URL: https://www.adcis.net/en/third-party/e-ophtha
  15. Kaggle. APTOS 2019 Blindness Detection. URL: https://www.kaggle.com/competitions/aptos2019-blindness-detection
  16. Indian Diabetic Retinopathy Image Dataset (IDRID). URL: https://ieee-dataport.org/open-access/indian-diabetic-retinopathy-image-dataset-idrid
  17. ADCIS. MESSIDOR-2 Dataset. URL: https://www.adcis.net/en/third-party/messidor2/
  18. High-Resolution Fundus (HRF) Image Database. URL: https://www5.cs.fau.de/research/data/fundus-images/
  19. D. S. Kermany, “Identifying Medical Diagnoses and Treatable Diseases by Image-Based Deep Learning”, Cell, vol. 172, no. 5, pp. 1122–1131.e9, Feb. 2018. DOI: https://doi.org/10.1016/j.cell.2018.02.010
  20. D. S. W. Ting, “Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes”, JAMA, vol. 318, no. 22, p. 2211, Dec. 2017. DOI: https://doi.org/10.1001/jama.2017.18152
  21. Sayres, R., Taly, A., Rahimy, E., Blumer, K., Coz, D., Hammel, N., Krause, J., Narayanaswamy, A., Rastegar, Z., Wu, D., Xu, S., Barb, S., Joseph, A., Shumski, M., Smith, J., Sood, A. B., Corrado, G. S., Peng, L., & Webster, D. R. (2019). Using a Deep Learning Algorithm and Integrated Gradients Explanation to Assist Grading for Diabetic Retinopathy. Ophthalmology, 126(4), 552–564. DOI: https://doi.org/10.1016/j.ophtha.2018.11.016
  22. M. D. Abràmoff, P. T. Lavin, M. Birch, N. Shah, and J. C. Folk, “Pivotal trial of an autonomous AI-based diagnostic system for detection of diabetic retinopathy in primary care offices”, npj Digital Medicine, vol. 1, no. 1, Aug. 2018. DOI: https://doi.org/10.1038/s41746-018-0040-6
  23. Y. Jiang, J. Liang, T. Cheng, X. Lin, Y. Zhang, and J. Dong, “MTPA_Unet: Multi-Scale Transformer-Position Attention Retinal Vessel Segmentation Network Joint Transformer and CNN”, Sensors, vol. 22, no. 12, p. 4592, Jun. 2022. DOI: https://doi.org/10.3390/s22124592
  24. L. Wewetzer, L. A. Held, J. Steinhäuser, and D. A. Worthy, “Diagnostic performance of deep-learning-based screening methods for diabetic retinopathy in primary care—A meta-analysis”, PLOS ONE, vol. 16, no. 8, p. e0255034, Aug. 2021. DOI: https://doi.org/10.1371/journal.pone.0255034
  25. N. Tsiknakis, “Deep learning for diabetic retinopathy detection and classification based on fundus images: A review”, Computers in Biology and Medicine, vol. 135, p. 104599, Aug. 2021. DOI: https://doi.org/10.1016/j.compbiomed.2021.104599
  26. M. S. Patil, S. Chickerur, C. Abhimalya, A. Naik, N. Kumari, and S. Maurya, “Effective Deep Learning Data Augmentation Techniques for Diabetic Retinopathy Classification”, Procedia Computer Science, vol. 218, pp. 1156–1165, Jan. 2023. DOI: https://doi.org/10.1016/j.procs.2023.01.094
  27. X. Guo, X. Lu, B. Zhang, X. Hu, and S. Che, “AUTOMATIC DETECTION AND GRADING OF DIABETIC MACULAR EDEMA BASED ON A DEEP NEURAL NETWORK”, Retina, vol. 42, no. 6, pp. 1095–1102, Jun. 2022. DOI: https://doi.org/10.1097/IAE.0000000000003434
  28. M. Kim and H.-J. Bae, “Data Augmentation Techniques for Deep Learning-Based Medical Image Analyses”, Journal of the Korean Society of Radiology, vol. 81, no. 6, p. 1290, Jan. 2020. DOI: https://doi.org/10.3348/jksr.2020.0158
  29. J.-G. Lee, “Deep Learning in Medical Imaging: General Overview”, Korean Journal of Radiology, vol. 18, no. 4, p. 570, Jan. 2017 DOI: https://doi.org/10.3348/kjr.2017.18.4.570
  30. A. M. Mutawa, K. Al-Sabti, S. Raizada, and S. Sruthi, “A Deep Learning Model for Detecting Diabetic Retinopathy Stages with Discrete Wavelet Transform”, Applied Sciences, vol. 14, no. 11, p. 4428, May 2024. DOI: https://doi.org/10.3390/app14114428
§ 06 — Related

Similar articles in this journal

Related peer-reviewed studies published in this journal.
View all issues

Software Support for the Higher Mathematics Course at the Technical University: Part 3. GNU Octave

Dmytro Voitsikh, Danylo Hryn, Mariia Hryniuk, PhD, Assoc. Prof. Oleksii Viktorovych Bogdanov, PhD, Assoc. Prof. Yurii Pavlovych Butsenko, PhD, Assoc. Prof. Olena Ivanivna Balina, PhD, Assoc. Prof. Iryna Srhiivna Bezklubenko

This paper explores a methodological approach to modernizing the higher mathematics curriculum for engineering students, with a specific focus on the needs of “G5…

#Engineering education #Teaching engineering #Electronics engineering #GNU Octave
p. 359022.1-359022.10
10.20535/2523-4455.mea.359022

Most read articles by the same author(s)

Similar Articles

1-10 of 34

You may also start an advanced similarity search for this article.